DOWNSTREAM MIGRATION: PROBLEMS AND FACILITIES

FMNL2 Drives Actin-Based Protrusion and Migration Downstream of Cdc42

Cell migration entails protrusion of lamellipodia, densely packed networks of actin filaments at the cell front. Filaments are generated by nucleation, likely mediated by Arp2/3 complex and its activator Scar/WAVE. It is unclear whether formins contribute to lamellipodial actin filament nucleation or serve as elongators of filaments nucleated by Arp2/3 complex. Here we show that the Diaphanous-...

Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling

Toddler/Apela/Elabela is a conserved secreted peptide that regulates mesendoderm development during zebrafish gastrulation. Two non-exclusive models have been proposed to explain Toddler function. The 'specification model' postulates that Toddler signaling enhances Nodal signaling to properly specify endoderm, whereas the 'migration model' posits that Toddler signaling regulates mesendodermal c...

Controlling Odor and Gaseous Emission Problems from Industrial Swine Facilities

Oral and Nutritional Problems among Residents in Assisted Living Facilities

Mathematical Programming Models for Solving Unequal-Sized Facilities Layout Problems - a Generic Search Method

 This paper present unequal-sized facilities layout solutions generated by a genetic search program named LADEGA (Layout Design using a Genetic Algorithm). The generalized quadratic assignment problem requiring pre-determined distance and material flow matrices as the input data and the continuous plane model employing a dynamic distance measure and a material flow matrix are discussed. Computa...